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Breast Tumor Stiffness and Metastasis Risk Linked by Molecule's Movement

April 20, 2015

Breast Tumor Stiffness and Metastasis Risk Linked by Molecule's Movement

Researchers at the University of California, San Diego School of Medicine and Moores Cancer Center have discovered a molecular mechanism that connects breast tissue stiffness to tumor metastasis and poor prognosis. The study, published April 20 inNature Cell Biology, may inspire new approaches to predicting patient outcomes and halting tumor metastasis.“We’re finding that cancer cell behavior isn’t driven by just biochemical signals, but also biomechanical signals from the tumor’s physical environment,” said senior author Jing Yang, PhD, associate professor of pharmacology and pediatrics. Full Story


Micromotors. Heart on a chip. Social media epidemiology. A Research Expo recap.

April 20, 2015

Micromotors. Heart on a chip. Social media epidemiology. A Research Expo recap.

Micromotors that zoom through a mouse’s stomach. Heart tissues on a chip. Analysis of social media posts to prevent an increase in HIV infections. These were only a few of more than 200 posters on display at the Jacobs School’s Research Expo 2015 at the Price Center Ballroom on April 16.  Full Story


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April 17, 2015

Artificial Blood Vessel Lets Researchers Better Assess Clot Removal Devices

Researchers at the School of Medicine and the Institue of Engineering in Medicine at the University of California, San Diego have created an in vitro, live-cell artificial vessel that can be used to study both the application and effects of devices used to extract life-threatening blood clots in the brain. The artificial vessel could have significant implications for future development of endovascular technologies, including reducing the need for animal models to test new devices or approaches. Full Story


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April 8, 2015

Bioengineering Day 2015: Bridging Bench to Bedside

On April 18th, 2015, the bioengineering department at the UC San Diego Jacobs School of Engineering will celebrate its 9th Annual Bioengineering Day. The event brings faculty, alumni, undergraduate and graduate students and industry partners together to discuss the yearly progress and successes within the bioengineering ecosystem at the Jacobs School of Engineering and the broader UC San Diego community. Full Story


Engineers will Pioneer the Future of Medicine

April 1, 2015

Engineers will Pioneer the Future of Medicine

Many of tomorrow’s solutions to today’s challenges in medicine will require feats of engineering in addition to biology, chemistry and health sciences. In fact, inventions such as valve prostheses, vascular stents and heart rhythm control systems are examples of how biology and medicine can work together with engineering to improve processes for maintaining health and quality of life. Full Story


Two Jacobs School of Engineering Faculty Members Receive NSF Engineering CAREER Award

March 26, 2015

Two Jacobs School of Engineering Faculty Members Receive NSF Engineering CAREER Award

Two UC San Diego Jacobs School of Engineering faculty members, Drew Hall, Assistant Professor of Electrical and Computer Engineering and Christian Metallo, Assistant Professor of Bioengineering have received the NSF Engineering CAREER Award.  Full Story


Bioengineering Graduate Program at UC San Diego Ranked #2 in Nation according to US News and World Report

March 10, 2015

Bioengineering Graduate Program at UC San Diego Ranked #2 in Nation according to US News and World Report

The bioengineering graduate program at the University of California, San Diego ranks #2 in the nation. This is one of the new rankings from the 2016 edition of U.S. News & World Report’s Best Graduate Schools guidebook, released today.  Full Story


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March 2, 2015

Three Jacobs School engineers honored as Sloan Fellows

Three engineers at the University of California, San Diego, are being honored by the Alfred P. Sloan Foundation with Sloan Research Fellowships for 2015. This year’s recipients are computer scientist Shachar Lovett, Padmini Rangamani, from the Department of Mechanical and Aerospace Engineering, and nanoengineer Andrea Tao.The fellowships seek to boost fundamental research by early-career scientists and scholars of outstanding promise. The two-year awards go to 126 researchers yearly in recognition of distinguished performance and a unique potential to make substantial contributions to their field."Their achievements and potential place them among the next generation of scientific leaders in the U.S. and Canada," noted the Foundation in a full-page New York Times advertisement, adding that since 1955, "Sloan Research Fellows have gone on to win 43 Nobel Prizes, 16 Fields Medal, 65 National Medals of Science" and numerous other honors. Full Story


Engineers Put the 'Squeeze' on Human Stem Cells

February 9, 2015

Engineers Put the 'Squeeze' on Human Stem Cells

After using optical tweezers to squeeze a tiny bead attached to the outside of a human stem cell, researchers now know how mechanical forces can trigger a key signaling pathway in the cells. The squeeze helps to release calcium ions stored inside the cells and opens up channels in the cell membrane that allow the ions to flow into the cells, according to the study led by University of California, San Diego bioengineer Yingxiao WangFull Story


Two UC San Diego Scientists Receive Stem Cell Technology Grants

February 3, 2015

Two UC San Diego Scientists Receive Stem Cell Technology Grants

The governing board of the California Institute for Regenerative Medicine (CIRM) has awarded two University of California, San Diego researchers almost $3 million in combined funding to pursue new technologies intended to accelerate advances moving stem cell therapies out of the lab and into the clinic. Full Story


NSF grant to improve visualization capabilities for the biosciences and geosciences

December 17, 2014

NSF grant to improve visualization capabilities for the biosciences and geosciences

The National Center for Atmospheric Research (NCAR) is partnering with the University of California, San Diego (UC San Diego), to expand and enhance visualization capabilities in the bio- and geosciences through a grant from the National Science Foundation. Full Story


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December 8, 2014

A Sampler of Exciting Stories from 2014 from the UC San Diego Jacobs School of Engineering

From robots to rockets and crowdfunding to cybersecurity, 2014 has been a busy year here at the Jacobs School of Engineering at UC San Diego. Below is a sample of the highlights of the past 12 months. (Be sure to check the Jacobs School press release archive for 2014, Jacobs School blog, and archive of press clips highlighting Jacobs School projects for a more comprehensive list.) Full Story


Bioengineering Study Finds Two-Cell Mouse Embryos Already Talking about Their Future

November 25, 2014

Bioengineering Study Finds Two-Cell Mouse Embryos Already Talking about Their Future

Bioengineers at the University of California, San Diego have discovered that mouse embryos are contemplating their cellular fates in the earliest stages after fertilization when the embryo has only two to four cells, a discovery that could upend the scientific consensus about when embryonic cells begin differentiating into cell types. Full Story


Vegetable Oil Ingredient Key to Destroying Gastric Disease Bacteria

November 24, 2014

Vegetable Oil Ingredient Key to Destroying Gastric Disease Bacteria

The bacterium Helicobacter pylori is strongly associated with gastric ulcers and cancer. To combat the infection, researchers at University of California, San Diego School of Medicine and Jacobs School of Engineering developed LipoLLA, a therapeutic nanoparticle that contains linolenic acid, a component in vegetable oils. In mice, LipoLLA was safe and more effective against H. pylori infection than standard antibiotic treatments.The results are published online Nov. 24 in the Proceedings of the National Academy of Sciences. Full Story


Shu Chien Receives U.C. San Diego Roger Revelle Medal

November 20, 2014

Shu Chien Receives U.C. San Diego Roger Revelle Medal

University of California, San Diego bioengineering professor Shu Chien has received the Roger Revelle Medal from UC San Diego Chancellor Pradeep K. Khosla with the citation: “Shu Chien is widely known as an exceptional researcher, instructor, mentor and citizen of the university and his professional community.”  Full Story


Engineering Graduate Students Named Siebel Scholars

November 7, 2014

Engineering Graduate Students Named Siebel Scholars

Five engineering graduate students from the University of California, San Diego have been named 2015 Siebel Scholars. Full Story


Engineers and physicians propose new approach to single-ventricle heart surgery for infants

November 5, 2014

Engineers and physicians propose new approach to single-ventricle heart surgery for infants

A schematic of an industrial ejector pump. This device transfers the energy of flow withhigher pressure to the flow with lower pressure, hence elevating the pressure at the outlet. Based onthe same concept, flow through the SVC can be assisted by flow through the shunt to obtain a higherpressure at the PA without increasing SVC Full Story


Nineteen new faculty join the Jacobs School of Engineering at UC San Diego

October 16, 2014

Nineteen new faculty join the Jacobs School of Engineering at UC San Diego

Nineteen new faculty members will join the Jacobs School of Engineering this year, which is growing to meet the intense demand for its engineering education programs.  Full Story


Biomedical Engineers Win 'People's Choice' Award for Inspiring Video

October 3, 2014

Biomedical Engineers Win 'People's Choice' Award for Inspiring Video

The National Academy of Engineering named a group of University of California, San Diego bioengineering students as the “People’s Choice” award winner in a video contest celebrating the 50th anniversary of the NAE. The Biomedical Engineering Society at UC San Diego received $5,000 in prize money for their award-winning video titled “The Future is Boundless.” Full Story


Diabetes in a Dish

October 2, 2014

Diabetes in a Dish

Although type 1 diabetes can be controlled with insulin injections and lifestyle modifications, major advances in treating the disease have not been made in more than two decades and there remain fundamental gaps in what is understood about its causes and how to halt its progression.With a 5-year, $4-million grant from the National Institutes of Health, researchers at University of California, San Diego School of Medicine and bioengineers at UC San Diego Jacobs School of Engineering, with colleagues at UC Irvine and Washington University in St. Louis hope to change this. Full Story