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This Injected Protein-like Polymer Helps Tissues Heal After a Heart Attack

April 25, 2025

This Injected Protein-like Polymer Helps Tissues Heal After a Heart Attack

Researchers have developed a new therapy that can be injected intravenously right after a heart attack to promote healing and prevent heart failure.  The therapy both prompts the immune system to encourage tissue repair and promotes survival of heart muscle cells after a heart attack. Researchers tested the therapy in rats and showed that it is effective up to five weeks after injection.    Full Story


AI Helps Unravel a Cause of Alzheimer's Disease and Identify a Therapeutic Candidate

April 25, 2025

AI Helps Unravel a Cause of Alzheimer's Disease and Identify a Therapeutic Candidate

A new study found that a gene recently recognized as a biomarker for Alzheimer’s disease is actually a cause of it, due to its previously unknown secondary function that triggers a pathway that disrupts how cells in the brain turn genes on and off. Full Story


Childhood Exposure to Bacterial Toxin May Be Triggering Colorectal Cancer Epidemic Among the Young

April 23, 2025

Childhood Exposure to Bacterial Toxin May Be Triggering Colorectal Cancer Epidemic Among the Young

In an effort to explain a modern medical mystery, an international team of researchers led by bioengineers at the University of California San Diego has identified a potential microbial culprit behind the alarming rise in early-onset colorectal cancer: a bacterial toxin called colibactin. Full Story


UC San Diego Bioengineer Inducted Into 2025 Class of the AIMBE College of Fellows

March 31, 2025

UC San Diego Bioengineer Inducted Into 2025 Class of the AIMBE College of Fellows

Bioengineering professor Daniela Valdez-Jasso was inducted into the College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE). She was recognized for her research exploring the roles of biomechanical forces in the progression of pulmonary arterial hypertension. Full Story


Bioengineer Elected AAAS Fellow

March 27, 2025

Bioengineer Elected AAAS Fellow

Karen Christman, a professor in the Shu Chien-Gene Lay Department of Bioengineering and the Sanford Stem Cell Institute, was elected a 2024 AAAS Fellow.  Full Story


How a Y Chromosome Gene May Shape the Course of Heart Valve Disease

March 20, 2025

How a Y Chromosome Gene May Shape the Course of Heart Valve Disease

Bioengineers have shed new light on how a type of heart valve disease—aortic valve stenosis—progresses differently in males and females. The research paves the way for treatments that can be tailored to a patient's biological sex. Full Story


Sam Ward Appointed Vice Dean for Research at School of Medicine

March 10, 2025

Sam Ward Appointed Vice Dean for Research at School of Medicine

Sam Ward, P.T., Ph.D., professor in the Departments of Orthopaedic Surgery and Radiology at the University of California San Diego School of Medicine and Bioengineering at the UC San Diego Jacobs School of Engineering, has been appointed vice dean for research. Full Story


A New Way to Predict Cancer's Spread? Scientists Look at 'Stickiness' of Tumor Cells

March 5, 2025

A New Way to Predict Cancer's Spread? Scientists Look at 'Stickiness' of Tumor Cells

By assessing how "sticky" tumor cells are, UC San Diego researchers have found a potential way to predict whether a patient's early-stage breast cancer is likely to spread. The discovery could help doctors identify high-risk patients and tailor their treatments accordingly. Full Story


Color Block

February 27, 2025

Bioengineer elected to the National Academy of Inventors

Lingyan Shi was elected as a senior member of the National Academy of Inventors. She is an expert in imaging and spectroscopy technologies, such as stimulated Raman scattering (SRS) nanoscopy. This imaging technique can visualize chemical signatures such as molecular bonds in cells, tissues or animals without the need for fluorescent markers typically used in biological microscopy. The technology can be a powerful tool for diagnosing and assessing the impact of therapies for neurodegenerative diseases, cancer and aging processes, as well as for drug discovery. Full Story


UC San Diego Professor Honored by Sony and Nature for Bioengineering Research

February 5, 2025

UC San Diego Professor Honored by Sony and Nature for Bioengineering Research

Bioengineering Professor Kiana Aran is one of three inaugural winners of the Sony Women in Technology Award with Nature. She is recognized for her pioneering work fusing biology with electronics to enhance precision medicine—including the development of CRISPR-Chip, a CRISPR-powered electronic chip designed to detect genetic mutations in real time. The award is a collaboration between the Sony Group Corporation and Nature. Full Story


Scaling up Neuromorphic Computing for More Efficient and Effective AI Everywhere and Anytime

January 23, 2025

Scaling up Neuromorphic Computing for More Efficient and Effective AI Everywhere and Anytime

Neuromorphic computing—a field that applies principles of neuroscience to computing systems to mimic the brain’s function and structure—needs to scale up if it is to effectively compete with current computing methods. In a review published Jan. 22 in the journal Nature, 23 researchers, including two from the University of California San Diego, present a detailed roadmap of what needs to happen to reach that goal. The article offers a new and practical perspective toward approaching the cognitive capacity of the human brain with comparable form factor and power consumption.    Full Story


Why Our Biological Clock Ticks: Research Reconciles Major Theories of Aging

January 21, 2025

Why Our Biological Clock Ticks: Research Reconciles Major Theories of Aging

Researchers at UC San Diego have published results that shed new light on an old question: what causes aging at the molecular level? Their findings, published in Nature Aging, describe a never-before-seen link between the two most accepted explanations: random genetic mutations and predictable epigenetic modifications.  Full Story


Jacobs School Faculty Receive Awards to Accelerate Innovation to Market

January 16, 2025

Jacobs School Faculty Receive Awards to Accelerate Innovation to Market

Stephanie Fraley, Nicole Steinmetz, Kiana Aran and Sheng Xu all received Accelerating Innovation to Market awards from the Office of Innovation and Commercialization. In addition, Jacobs School affiliates Erin Walsh and Nadir Weibel also received awards.  Full Story


Genetic Tweak Optimizes Drug-making Cells by Blocking Buildup of Toxic Byproduct

January 14, 2025

Genetic Tweak Optimizes Drug-making Cells by Blocking Buildup of Toxic Byproduct

Scientists led by UC San Diego have developed a new strategy to enhance pharmaceutical production in Chinese hamster ovary (CHO) cells, which are commonly used to manufacture protein-based drugs for treating cancer, autoimmune diseases and much more. By knocking out a gene circuit responsible for producing lactic acid—a metabolite that makes the cells’ environment toxic—researchers eliminate a primary hurdle in developing cells that can produce higher amounts of pharmaceuticals like Herceptin and Rituximab, without compromising their growth or energy production. Full Story


Nanoscale Bumps and Grooves Trigger Big Changes in Cell Behavior

December 3, 2024

Nanoscale Bumps and Grooves Trigger Big Changes in Cell Behavior

The surfaces that cells come into contact with can influence how the cells grow, function, and communicate — shaping metabolism and even cellular health. Now, engineering researchers at the University of California San Diego have developed a platform for studying the ways that nanoscale growing surfaces can impact cellular behavior. Full Story


How Artificial Intelligence Could Automate Genomics Research

December 2, 2024

How Artificial Intelligence Could Automate Genomics Research

Researchers at University of California San Diego School of Medicine have demonstrated that large language models (LLMs), such as GPT-4, could help automate functional genomics research, which seeks to determine what genes do and how they interact.  Full Story


UC San Diego Part of National Hub for Large-scale Neuromorphic Computing

November 1, 2024

UC San Diego Part of National Hub for Large-scale Neuromorphic Computing

Bioengineering professor Gert Cauwenberghs at the University of California San Diego is one of four researchers leading a new hub that will provide access to open and heterogeneous neuromorphic computing hardware systems. The Neuromorphic Commons Hub, also known as THOR, is based at the University of Texas San Antonio and funded by a $4 million grant from the National Science Foundation. It aims to deploy and manage a large-scale community research infrastructure. Full Story


Digestive Enzyme Escaping from the Gut and into Many Organs May Cause Aging in Rats

October 28, 2024

Digestive Enzyme Escaping from the Gut and into Many Organs May Cause Aging in Rats

The mucosal layer in the small intestine degrades with age in rats, allowing digestive enzymes to slowly escape and leak into organs outside the intestine, including the liver, lung, heart, kidney and brain.  Full Story


Four UC San Diego Startups to Watch from Innovation Day 2024

October 3, 2024

Four UC San Diego Startups to Watch from Innovation Day 2024

They’re developing new therapeutics and treatments for cancer patients, building artificial intelligence personas to maximize employee efficiency and creating cutting-edge tools to reduce pesticide use—and they’re all powered by the University of California San Diego’s world-class innovation ecosystem. Full Story


UC San Diego Named Nation's 6th Best Public University by U.S. News & World Report

September 24, 2024

UC San Diego Named Nation's 6th Best Public University by U.S. News & World Report

Four Jacobs School undergraduate engineering and computer science programs are ranked Top 10 in the country in the latest from U.S. News & World Report. Full Story